Peptides and eptidomimetic therapeutics: scientific approaches (6 CFU)
Prof. Simona Collina
Aims and contents. This three-days course focuses on the peptides and peptidomimetics therapeutics, Editing naturally occurring peptide sequences to develop peptidomimetic analogs created a promising class of therapeutics that can augment or inhibit molecular interactions. A variety of chemical modifications, and design strategies, such as attachment to cell-penetrating peptides, which are used to develop peptidomimetics will be discussed as well as structural modifications suitable to improve their pharmacodynamic, pharmacokinetic and toxicological profiles. Theoretical lessons are combined with practical case studies.
Learning ability test: oral examination